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 | Mitochondrial Membrane Permeability Transition Kits |  | | | | | |
| Assess Mitochondrial Membrane Potential Detection of the mitochondrial permeability transition event (PT) provides an early indication of the initiation of cellular apoptosis. This process is typically defined as a collapse in the electrochemical gradient across the mitochondrial membrane, as measured by the change in the membrane potential.
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| ![AWT IMAGE]() | Kit Features Easy | Just add directly to the media; healthy cells will fluoresce orange/red | Fast | Typical incubation is 15-20 minutes | Accurate | Orange/red signal is reduced in dying cells | Sensitive | Easily distinguish positive from negative populations | Quantitative | Analyze with a flow cytometer, fluorescence plate reader, or fluorescence microscope | Allows Whole Cell Analysis | The reagents are cell-permeant so you do not have to lyse the cells |
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| About ICT...
Based in Bloomington, Minnesota, ICT is one of the world's leading suppliers of unique in vivo and in vitro tools critical for discovering promising investigational medicines for treating life threatening illnesses.
Our fluorescent enzyme detection probes are used to assess apoptosis and cell death in cultured cells. ICT's specialty in vitro probes detect caspases, cathepsins, serine proteases, cholinesterase enzymes, and assess mitochondrial health.
We also manufature proprietary probes that can detect dead and dying cells in living organisms in vivo for research use. In the future, these probes may be used to better manage disease and personalize treatment. ICT's in vivo probes may be used to assess the efficacy of chemotherapy, to quantify neurodegeneration, and as an early detector of eye disease, among other applications.
ICT is also a contract research laboratory specializing in custom ELISA development, manufacturing, and testing services. As an out-growth of these services, ICT offers a specialty line of ELISA buffers and stabilizers to researchers making in-house assays. | | | |
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| | | دفعات مشاهده: 1492 بار | دفعات چاپ: 541 بار | دفعات ارسال به ديگران: 232 بار | 0 نظر | |
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